Infiltration of an adjuvant drug with local anaesthetic for post operative pain relief in lower abdominal surgries

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2019/08/020674

Lead Sponsor: Department of Health and Family Welfare

Brief Summary: This is a prospective randomized study for post operative analgesic efficacy of wound infiltration of bupivacaine alone and with combinations of two comparative doses of dexmedetomidine.

The post operative analgesia upto 48hours post operative period is observed and also the time for first rescue analgesia ( inj tramadol in our study) is observed.

75 study patients divided randomly into 3 groups (25 in each group)

**GroupB** = Inj.Bupivacaine Hydrochloride 0.25% 18 ml + Placebo (Normal Saline 0.9%) 2 ml 0.9%NS

**GroupBD(I)**= Inj. Bupivacaine Hydrochloride 0.25% 18 ml + Inj.Dexmetedomine 0.5 mcg/kg 2 ml 0.9% NS

**GroupBD(II)**= Inj. Bupivacaine Hydrochloride 0.25% 18 ml + Inj.Dexmetedomine 1 mcg/kg 2 ml 0.9% NS

Ã˜ Thehypothesis of our study is that dexmedetomedine when added as an adjuvant tobupivacaine in wound infiltration in lower abdominal surgries, potentiatesaction of bupivacaine and duration of post operative pain relief will be longeras compared to bupivacaine alone.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 75

Inclusion Criteria

ASA I & II SCHEDULED FOR LOWER ABDOMINAL SURGERIES.

Exclusion Criteria

Patient refusal Patients with H/o cardiac, respiratory, renal or hepatic dysfunction or failure Coagulation disorders Psychological disorders Allergy to study medications Chronic use of pain medications Adrenoreceptors agonists or antagonists Patients with H/o Motion sickness Patient with Body mass index > 35 Women who are in menstruation.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
duration and efficiency of post operative analgesia after wound infiltration	duration of post operative analgesia 48 hour after wound infiltration

Secondary Outcome Measures

Name	Time	Method
The effectiveness and onset of post operative analgesia,sedation and complications if any.	48 hour post operative period

Trial Locations

Locations (1): Civil hospital Bj medical college ahmdabad
🇮🇳
Ahmadabad, GUJARAT, India
Civil hospital Bj medical college ahmdabad
🇮🇳Ahmadabad, GUJARAT, India
Mona Bilandani
Principal investigator
9408353053
bilandanim@yahoo.co.in