Calorie restriction and plasma brain-derived neurotrophic factor
Not Applicable
- Conditions
- Hypertension.Essential (primary) hypertension
- Registration Number
- IRCT20160702028742N11
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Patients with a body mass index higher than 25
Regular use of antihypertensive drugs for at least the last 3 months
non-smoker
Haven't been under any weight-loss diet at least 3 months before participating in the study
Exclusion Criteria
Taking antipsychotic, anticonvulsant drugs
Cancer or stage 4 or 5 chronic or kidney disease
Pregnancy or breastfeeding
Any changes in the disease treatment plan during the study, including changes in the type and dose of drugs used to affect blood pressure or surgery•
Insulin treated patients
Taking omega 3 supplement
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure. Timepoint: Baseline and the end of study. Method of measurement: Validated digital arm sphygmomanometer.
- Secondary Outcome Measures
Name Time Method Plasma brain-derived neurotrophic factor. Timepoint: Baseline and the end of study. Method of measurement: ?»]??.;Plasma ICAM-1. Timepoint: Baseline and the end of study. Method of measurement: ELISA.