Development and Prospective Validation of an Artificial Intelligence Model to Predict Postoperative Acute Kidney Injury
试验速览
- 阶段
- 不适用
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- the incidence of postoperative acute kidney injury
研究概览
简要总结
The main objective of this study is to develop and validate an artificial intelligence model that predicts postoperative acute kidney injury.
详细描述
Postoperative acute kidney injury is known to increase the length of hospital stay and healthcare cost. A lot of risk prediction models have been developed for identifying patients at increased risk of postoperative acute kidney injury. Recent advances in artificial intelligence make it possible to manage and analyze big data. Prediction model using an artificial intelligence and large-scale data can improve the accuracy of prediction performance. Furthermore, the use of an artificial intelligence may be a useful adjuvant tool in making clinical decisions or real-time prediction if it is integrated into the electrical medical record systems. However, before implementing an artificial intelligence model into the clinical setting, prospective evaluation of an artificial intelligence model's real performance is essential. However, to our knowledge, there was no artificial intelligence model for prediction of postoperative acute kidney injury, which was prospectively evaluated. Therefore, we aimed to develop an artificial intelligence model which predicts postoperative acute kidney injury and evaluate the model's performance prospectively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults patients undergoing non-cardiac surgery
排除标准
- •Age under 18 years
- •Surgery duration < 1 hour
- •Transplantation surgery
- •Nephrectomy
- •Cardiac surgery
- •Patients who had severe kidney dysfunction preoperatively as follows:
- •Serum creatinine ≥ 4 mg/dl
- •Estimated glomerular filtration rate <15 ml/min/1.73m2
- •History of renal replacement therapy
- •Patients who had no results of preoperative or postoperative serum creatinine
结局指标
主要结局
the incidence of postoperative acute kidney injury
时间窗: during the postoperative seven days
postoperative acute kidney injury (diagnosed by KDIGO criteria using peak serum creatinine level) included all acute kidney injury events regardless of acute kidney injury severity
次要结局
未报告次要终点
研究者
Hyung-Chul Lee
Assistant professor
Seoul National University Hospital
