MedPath

CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies

Not Applicable
Completed
Conditions
Schizo Affective Disorder
Bipolar Disorder
Psychosis
Schizophrenia
Depressive Disorder
Registration Number
NCT05127837
Lead Sponsor
University of Washington
Brief Summary

The primary objective of this grant is to develop and evaluate an Artificial Intelligence-based clinical training tool--CBTpro--to support high-quality skills training in CBT for psychosis (CBTp). CBTpro will provide a rapid means of scaling and sustaining high-quality CBTp in routine care settings across the US.

Detailed Description

This fast-track Small Business Technology Transfer (STTR) grant is a partnership between the University of Washington and private company LYSSN that includes the development and iterative testing of CBTpro, a Computerized Clinician Support Tool designed to teach behavioral health providers and students Cognitive Behavioral Therapy for psychosis (CBTp). CBTpro uses natural language processing to provide automated speech-to-text and machine learning to score trainee's responses to simulated patients with psychosis.

Once technical reliability of the tool is achieved through iterative modifications based on usability and field trials, a randomized control trial will be conducted to assess CBTpro training vs. training as usual with N=100 providers / N=300 clients on clinician skills and client outcomes.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
379
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change in Green Paranoid Thoughts Scale (GPTS) Total Score0,3,6 months

The Green Paranoid Thoughts Scale (GPTS) is a 32-item self-report questionnaire designed to assess paranoid ideation over the past month. It consists of two 16-item subscales: Part A: Ideas of Social Reference and Part B: Persecutory Ideas. Each item is rated on a 5-point Likert scale from 1 ("Not at all") to 5 ("Totally"). Subscale scores range from 16 to 80, and the total score ranges from 32 to 160, with higher scores indicating more severe paranoid thinking. A reduction in total or subscale scores indicates improvement in paranoid ideation.

Secondary Outcome Measures
NameTimeMethod
Change in CHOICE-SF (Choice of Outcome in CBT for Psychosis- Short Form)0,3,6 months

The CHOICE-SF is a 12-item self-report questionnaire designed to assess perceived progress toward recovery among individuals receiving cognitive behavioral therapy for psychosis (CBTp). Each item is rated on a scale from 0 ("Not at all") to 10 ("Extremely") with the exception of the final question which is open-entry. Total scores range from 0 to 110, with higher scores reflecting greater perceived progress in psychological recovery. An increase in the CHOICE-SF score indicates improvement in recovery; a decrease suggests reduced perceived progress.

Change in in Sheehan Disability Scale (SDS) Total Score0,3,6 months

The Sheehan Disability Scale (SDS) is a 3-item self-report measure that assesses functional impairment in three domains: work/school, social life, and family life/home responsibilities. Each item is rated on an 11-point scale from 0 ("Not at all impaired") to 10 ("Extremely impaired"). The total score ranges from 0 to 30, with higher scores indicating greater functional impairment. A decrease in the total score reflects improved functioning.

Trial Locations

Locations (13)

South Central Health and Rehabilitation Programs

🇺🇸

Los Angeles, California, United States

Telecare

🇺🇸

San Jose, California, United States

Integrated Services of Kalamazoo

🇺🇸

Kalamazoo, Michigan, United States

Community Mental Health Authority of Clinton, Eaton, and Ingham Counties (CEICMH)

🇺🇸

Lansing, Michigan, United States

Coleman Health Services

🇺🇸

Akron, Ohio, United States

PeaceHealth

🇺🇸

Eugene, Oregon, United States

Cascadia

🇺🇸

Portland, Oregon, United States

Psynergy

🇺🇸

Morgan Hill, California, United States

Lifeworks NW

🇺🇸

Portland, Oregon, United States

Harborview Medical Center

🇺🇸

Seattle, Washington, United States

Scroll for more (3 remaining)
South Central Health and Rehabilitation Programs
🇺🇸Los Angeles, California, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.