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Clinical Trials/NCT05127837
NCT05127837
Completed
Not Applicable

Development of an Artificial Intelligence- Informed Digital Tool to Help Clinicians Practice Cognitive Behavioral Therapy for Psychosis (CBTp)

University of Washington13 sites in 1 country379 target enrollmentJune 28, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Psychosis
Sponsor
University of Washington
Enrollment
379
Locations
13
Primary Endpoint
Change in Green Paranoid Thoughts Scale (GPTS) Total Score
Status
Completed
Last Updated
11 months ago

Overview

Brief Summary

The primary objective of this grant is to develop and evaluate an Artificial Intelligence-based clinical training tool--CBTpro--to support high-quality skills training in CBT for psychosis (CBTp). CBTpro will provide a rapid means of scaling and sustaining high-quality CBTp in routine care settings across the US.

Detailed Description

This fast-track Small Business Technology Transfer (STTR) grant is a partnership between the University of Washington and private company LYSSN that includes the development and iterative testing of CBTpro, a Computerized Clinician Support Tool designed to teach behavioral health providers and students Cognitive Behavioral Therapy for psychosis (CBTp). CBTpro uses natural language processing to provide automated speech-to-text and machine learning to score trainee's responses to simulated patients with psychosis. Once technical reliability of the tool is achieved through iterative modifications based on usability and field trials, a randomized control trial will be conducted to assess CBTpro training vs. training as usual with N=100 providers / N=300 clients on clinician skills and client outcomes.

Registry
clinicaltrials.gov
Start Date
June 28, 2022
End Date
December 9, 2024
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sarah Kopelovich

Associate Professor of Psychiatry

University of Washington

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change in Green Paranoid Thoughts Scale (GPTS) Total Score

Time Frame: 0,3,6 months

The Green Paranoid Thoughts Scale (GPTS) is a 32-item self-report questionnaire designed to assess paranoid ideation over the past month. It consists of two 16-item subscales: Part A: Ideas of Social Reference and Part B: Persecutory Ideas. Each item is rated on a 5-point Likert scale from 1 ("Not at all") to 5 ("Totally"). Subscale scores range from 16 to 80, and the total score ranges from 32 to 160, with higher scores indicating more severe paranoid thinking. A reduction in total or subscale scores indicates improvement in paranoid ideation.

Secondary Outcomes

  • Change in CHOICE-SF (Choice of Outcome in CBT for Psychosis- Short Form)(0,3,6 months)
  • Change in in Sheehan Disability Scale (SDS) Total Score(0,3,6 months)

Study Sites (13)

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