Prognostic Value of Lactates in ICU

Completed

• Conditions: Mortality
• Interventions: Diagnostic Test: Blood lactate level

• Registration Number: NCT04792736
• Lead Sponsor: Mongi Slim Hospital

Brief Summary

he aim of this prospective, analytic trial was to evaluate the accuracy of blood lactates levels in predicting mortality in ICU patients.

Detailed Description

In this study, conducted over o 12 months period, arterial blood lactates levels were measured in ICU patients at admission (H0), every 6 hours during the first day and and H48.

This trial included traumatic, medical and surgical patients requiring ICU stay for a predictive period \> to 24 hours.

Blood lactates were evaluated as a prognostic parameter in predicting ICU mortality and compared to classic prognostic scores such as: SOFA score, IGS II and APACHE II.

The primary end point was ICU mortality.

Study Timeline

• Study Start: 2019-06-01
• Primary Completion: 2020-06-30
• Study Completion: 2020-07-31
• Status Verified: 2021-03
• Study First Submitted: 2021-03-08
• Study First Submitted QC: 2021-03-08
• Last Update Submitted: 2021-03-08
• Study First Posted: 2021-03-11
• Last Update Posted: 2021-03-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 135

Inclusion Criteria

• All adults admissions in ICU with a predicted length of stay > 24 hours

Exclusion Criteria

• Patients who died during the first 24 hours after ICU admission

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
non survivors	Blood lactate level	Patients who succumbed during their ICU stay
Survivors	Blood lactate level	Patients discharged alive from intensive care unit

Primary Outcome Measures

Name	Time	Method
ICU Mortality	28 days after ICU admission	Mortality at Day 28

Trial Locations

Locations (2)

Mongi Slim Hospital; 🇹🇳 Tunis, Tunisia

Mongi Slim University Hospital; 🇹🇳 La Marsa, Tunis, Tunisia