MedPath

blood lactate level as an indicator of low output syndrome in patients with heart failure

Not Applicable
Conditions
heart failure
Registration Number
JPRN-UMIN000012581
Lead Sponsor
ihon University Surugadai Hospital
Brief Summary

We conducted a research study to clarify whether blood lactate level has a predictive value for detecting LOS in patients with heart failure (HF) (n=32) who required single spot pulmonary artery catheter(PAC) study during treatment (average age; 66years, male; 69%). Blood lactate level showed significant correlations between stroke volume index and cardiac index (r=-0.49 p<0.01, r=-0.66 p<0.001, respectively). When the cut-off point of blood lactate level was 10 mg/dl, the sensitivity (88%) + specificity (96%) of the test was maximal, and the accuracy was 94% for the identification of low CI (below 2.2).

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

The patients who had active infectious disease or arterio-venous shunt

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Relation between blood lactate level and hemodynamic parameters obtained by pulmonary artery catheter
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath