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临床试验/NCT00344474
NCT00344474已完成2 期

A New School-based Drug Prevention Programme for Teenagers: Interventions That Target Personality Risk for Substance Abuse and Mental Illness

King's College London1 个研究点 分布在 1 个国家目标入组 710 人开始时间: 2003年11月1日最近更新:
适应症
干预措施

试验速览

阶段
2 期
状态
已完成
入组人数
710
试验地点
1
主要终点
Time to onset and severity of drug use

研究概览

简要总结

Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press). As these interventions target personality traits linked to risk for addictive and non-addictive mental disorders, the aim of this study is to examine the extent to which this approach can prevent and/or reduce alcohol and drug misuse as well as have an impact on the onset or severity of emotional and behavioural problems in young people.

详细描述

Personality targeted cognitive behavioural interventions have been shown to be effective in reducing alcohol and drug misuse in adult substance abusers (Conrod et al., 2000) and adolescent drinkers (Conrod et al, in press). As these interventions target personality traits linked to risk for addictive and non-addictive psychopathology, the aim of this study is to examine the extent to which this approach is effective in preventing and/or reduce alcohol and drug misuse and concurrent psychiatric symptoms in young people.

Method: 875 Participants aged 13-16 years will be screened for personality risk in school-wide self-report assessments. Participants will be randomly assigned to a personality matched cognitive-behavioural intervention or a no-intervention control. The personality matched interventions will target four personality risk factors: negative thinking (NT), anxiety sensitivity (AS), impulsivity (IMP) and sensation seeking (SS). Outcome evaluation will occur 6, 12, 18 and 24 months post intervention. Primary outcomes will be time to onset and severity of alcohol and illicit substance use and misuse. Secondary outcome variables will include depressive symptoms, panic attack rates, reckless and antisocial behaviour. Secondary analyses involving genetic, cognitive and coping skills measures will examine moderators of treatment effects.

Hypotheses: It is expected that personality-targeted interventions will have personality-specific effects on aspects of addictive and non-addictive psychopathology to which each personality risk group is most susceptible.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Prevention
盲法
None

入排标准

年龄范围
13 Years 至 16 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •secondary school student
  • •scoring one standard deviation above the school mean on one of 4 personality dimensions.
  • •Able to provide consent from parent/guardian for participation in the study

排除标准

  • 未提供

研究组 & 干预措施

learning to cope with your impulsivity

Experimental

cognitive behavioural intervention teaching high impulsive youth how to manage their impulsive thinking and behaviours

干预措施: PRE-Venture: Personality Risk Education (Behavioral)

learning to cope with your sensation seeking

Experimental

cognitive-behavioural intervention teaching high sensation seeking youth how to manage their need for stimulation and excitement

干预措施: PRE-Venture: Personality Risk Education (Behavioral)

learning to cope with your anxiety sensitivity

Experimental

cognitive behavioural intervention targeting catastrophic thinking in high anxiety sensitive youth

干预措施: PRE-Venture: Personality Risk Education (Behavioral)

learning to manage your negative thinking

Experimental

cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth

干预措施: PRE-Venture: Personality Risk Education (Behavioral)

结局指标

主要结局

Time to onset and severity of drug use

时间窗: 2 years

time to illicit drug use events, assessed using the Reckless Behaviour Questionnaire

Frequency and Quantity of Drinking

时间窗: 2 years

Problem drinking symptoms

时间窗: 2 years

Assessed using an abbreviated version of the Rutger's Alcohol Problem Index

次要结局

  • Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking(2 years)

研究者

申办方类型
Other

研究点 (1)

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