The Effect Of Antenatal Corticosteroids On Early And Late Perinatal Outcomes In Late Preterm Pregnant Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 459
- 试验地点
- 2
- 主要终点
- The results of antenatal corticosteroid effects
研究概览
简要总结
In this study, the investigators aims to evaluate whether antenatal corticosteroid administration to women likely to give birth in the late preterm period will reduce early and late neonatal complications and contribute to the literature in this sense.
详细描述
This study is a single-center prospective case-control study investigating the effect of antenatal corticosteroids administered in the late preterm period on early and late perinatal outcomes. 459 patients who gave birth between 34-37 weeks between June 1,2021 to October 1,2022 in the Obstetrics and Gynecology Clinic of the University of Health Sciences were included. Patient were divided into two groups antenatal corticosteroid administration (n:231) and non-administration (n:228). Postpartum early and late perinatal outcomes were compared between these two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •All pregnant women who had normal vaginal delivery, cesarean section or operative delivery between 34-37 weeks
- •Singleton pregnancies resulting in a live birth
排除标准
- •Twin pregnancies
- •All births before 34 weeks or after 37 weeks
- •Pregnant women with intrauterine ex fetus
- •Fetuses with major congenital and chromosomal abnormalities
- •Pregnant women who administrated antenatal corticosteroids for any reason before 34 weeks
结局指标
主要结局
The results of antenatal corticosteroid effects
时间窗: 16 months
intramuscular 3 mg betamethasone (dekort 8mg/2 ml) corticosteroid injection in perinatal period
次要结局
- Other consequences of antenatal corticosteroid effects in late term pregnant women(16 months)
研究者
Nefise Nazlı YENIGUL
Ph.D. Assistant Professor Department of Obstetrics and Gynecology
Bursa Yüksek İhtisas Education and Research Hospital