The Effect of Antenatal Corticosteroid Administration on Umbilical Artery Doppler Velocimetry in Pregnant Women Complicated With IUGR
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Intrauterine Growth Restriction
- Sponsor
- Merve Demir
- Enrollment
- 149
- Locations
- 1
- Primary Endpoint
- pulsatility index (PI)
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The purpose of this study is to evaluate the effect of antenatal corticosteroid administration on umbilical artery Doppler velocimetry measurements in pregnancies complicated by IUGR.
Detailed Description
This study was conducted with pregnant women who were likely to have preterm birth and were treated with antenatal corticosteroids. Betamethasone was used as an antenatal corticosteroid. UA Doppler measurements (PI, S/D ratio, RI) before antenatal corticosteroid administration and 24 and 48 hours after the last dose of corticosteroid administration were evaluated in pregnant groups complicated with IUGR and uncomplicated with IUGR and compared with each other.
Investigators
Merve Demir
Research assistant
Kocaeli University
Eligibility Criteria
Inclusion Criteria
- •pregnant women who were likely to have preterm delivery and were treated with antenatal corticosteroids.
Exclusion Criteria
- •Pregnant women who had complicated pregnancy with fetal anomaly, who had multiple pregnancies, who left their pregnancy follow-up unfinished, and those under 18 years of age were excluded from the study.
Outcomes
Primary Outcomes
pulsatility index (PI)
Time Frame: 2018-2019
Pulsatility Index (PI) = (Peak systolic velocity - end diastolic velocity)/(time averaged maximum velocity)
systolic:diastolic ratio (S/D ratio)
Time Frame: 2018-2019
Peak systolic velocity/end diastolic velocity
Resistive Index (RI)
Time Frame: 2018-2019
Resistive Index (RI) = (Peak systolic velocity - end diastolic velocity)/(peak systolic velocity)