The Effect of Antenatal Corticosteroid Administration on Umbilical Artery Doppler Velocimetry in Pregnant Women Complicated With IUGR
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 149
- 试验地点
- 1
- 主要终点
- pulsatility index (PI)
研究概览
简要总结
The purpose of this study is to evaluate the effect of antenatal corticosteroid administration on umbilical artery Doppler velocimetry measurements in pregnancies complicated by IUGR.
详细描述
This study was conducted with pregnant women who were likely to have preterm birth and were treated with antenatal corticosteroids. Betamethasone was used as an antenatal corticosteroid. UA Doppler measurements (PI, S/D ratio, RI) before antenatal corticosteroid administration and 24 and 48 hours after the last dose of corticosteroid administration were evaluated in pregnant groups complicated with IUGR and uncomplicated with IUGR and compared with each other.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 49 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •pregnant women who were likely to have preterm delivery and were treated with antenatal corticosteroids.
排除标准
- •Pregnant women who had complicated pregnancy with fetal anomaly, who had multiple pregnancies, who left their pregnancy follow-up unfinished, and those under 18 years of age were excluded from the study.
结局指标
主要结局
pulsatility index (PI)
时间窗: 2018-2019
Pulsatility Index (PI) = (Peak systolic velocity - end diastolic velocity)/(time averaged maximum velocity)
systolic:diastolic ratio (S/D ratio)
时间窗: 2018-2019
Peak systolic velocity/end diastolic velocity
Resistive Index (RI)
时间窗: 2018-2019
Resistive Index (RI) = (Peak systolic velocity - end diastolic velocity)/(peak systolic velocity)
次要结局
未报告次要终点
研究者
Merve Demir
Research assistant
Kocaeli University