Effects of ALB-PRF on bone formation when placed in immediate dental implant- A case control study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- ALB-PRF is effective in promoting bone formation
研究概览
简要总结
This study helps to find the effectiveness of ALB-PRF in promoting bone formation when placed in immediate dental implants.
In dental implants osseointegration and implant stability is prime concern and to enhance these bone grafts and blood concentrates are widely used.
Albumin-enriched biomaterials provide an optimal structure for cell proliferation and show minimal reduction over time, suggesting less in vitro degradation. Studies further suggest that the association with albumin can stabilize the fibrin network’s ultrastructure. In addition, preliminary data indicate that combining denatured serum albumin significantly enhances the PRF-based scaffold, yielding an autologous, biocompatible material with the potential enhance durability and sustained action.Additionally they release higher level of growth factors which enhance their therapeutic potential.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients between 30 and 60 years of age, having a hopeless mandibular tooth indicated for extraction (due to an unrestorable fracture or a carious lesion) requiring immediate dental implant placement.
- •The absence of any active infection, pus discharge and bone dehiscence on buccal wall of tooth socket.
- •Intact socket walls.
- •ASA Grade I and II.
排除标准
- •Aggressive periodontitis Medically compromised patients External root resorption Tobacco users Pregnant women.
结局指标
主要结局
ALB-PRF is effective in promoting bone formation
时间窗: ALB-PRF is effective in promoting bone formation in 8 weeks
次要结局
- ALB-PRF is effective in enhancing implant stability(ALB-PRF is effective in enhancing implant stability in)