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Electrophysiology in Congenital Cataract After Lensectomy and Anterior

Completed
Conditions
Congenital Cataract
Registration Number
NCT04427748
Lead Sponsor
Wenzhou Medical University
Brief Summary

In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test group, 25 normal eyes as control group. The a- and b-wave and PhNR related parameters was evaluated.

Detailed Description

Secondary IOL implantation in aphika children and lensectomy and anterior vitrectomy and primary IOL implantation in children with congenital cataract were both performed by the same surgeon(Z.Y.E).

electroretinography and photopic negative response are performed to each patient.The research was to evaluate the relationship between the best corrected visionn and the related parameters of a- and b-wave and PhNR .

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
116
Inclusion Criteria
  • phakic children diagnosed with congenital cataract who underwent secondary IOL implantation and children with congenital cataract who underwent lensectomy and anterior vitrectomy and primary IOL implantation
Exclusion Criteria
  • patients with mild cataracts do not require surgery

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ERGat least 1year after the surgery of congenital cataract

investigate retinal function changes of congenital cataract children. ERG related parameters including a- and b-wave and PhNR amplitude and latency.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Eye Hosptial of Wenzhou Medical College

🇨🇳

Wenzhou, Zhejiang, China

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