Prevalence of Endometriosis in a Well Defined Group of Infertile Women

Completed

• Conditions: Infertility; Endometriosis
• Interventions: Procedure: Laparoscopy

• Registration Number: NCT00464139
• Lead Sponsor: University Hospital, Gasthuisberg

Brief Summary

At the Leuven University Fertility Centre (LUFC) of the Department of Obstetrics and Gynecology of the University Hospitals Leuven, Belgium, a retrospective epidemiological prevalence study based on an electronic search of patient files was performed to determine the prevalence of histologically proven endometriosis in a subset of infertile women with a regular cycle (variation 21 - 35 days), a partner with normal sperm and no previous surgical diagnosis of endometriosis.

Detailed Description

In this study, the electronic files of all patients who consulted the LUFC since 2003 were searched to select women with at least 1 year of infertility, a regular cycle (variation 21 - 35 days), whose partner had normal sperm according to World Health Organization (WHO) criteria (n = 304).

After exclusion of 83 (27,3%) patients with a previous laparoscopic diagnosis of endometriosis before referral to our centre, 221 (72,7%) infertile women were included in our study.

Study Timeline

• Study Start: 2007-01
• Primary Completion: 2007-02
• Study Completion: 2007-02
• Study First Submitted: 2007-04-18
• Study First Submitted QC: 2007-04-18
• Study First Posted: 2007-04-20
• Status Verified: 2009-02
• Last Update Submitted: 2009-02-19
• Last Update Posted: 2009-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 221

Inclusion Criteria

• all patients who consulted the LUFC since 2003
• with at least 1 year of infertility,
• a regular cycle (variation 21 - 35 days),
• whose partner had normal sperm according to World Health Organization (WHO) criteria.

Exclusion Criteria

• a previous laparoscopic diagnosis of endometriosis before referral to our centre

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
1	Laparoscopy	The electronic files of all patients who consulted the LUFC since 2003 were searched to select women with at least 1 year of infertility, a regular cycle (variation 21 - 35 days), whose partner had normal sperm according to World Health Organization (WHO) criteria (n = 304). After exclusion of 83 (27,3%) patients with a previous laparoscopic diagnosis of endometriosis before referral to our centre, 221 (72,7%) infertile women were included in our study.

Primary Outcome Measures

Name	Time	Method
The diagnosis of endometriosis was made by the fertility surgeon of the LUFC.	2003 - 2006

Secondary Outcome Measures

Name	Time	Method
The diagnosis of endometriosis was always confirmed by histological examination.	2003 - 2006

Trial Locations

Locations (1)

University Hospital Gasthuisberg; 🇧🇪 Leuven, Belgium