NCT00323466已完成不适用
A Study of the Effect on Oro-dental Complications of Intensity Modulated Radiotherapy (IMRT) Versus Conventional Radiotherapy in Patients With Cancer of the Head or Neck
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 43
- 试验地点
- 2
- 主要终点
- Volume of saliva
研究概览
简要总结
Study to investigate the effect of two types of radiotherapy on saliva: IMRT versus conventional radiotherapy.
In each group, one part will receive normal dental preventive treatment. The other part will use products for treatment of dry mouth (Biotene gamma).
Both anorganic and organic components of the saliva will be studied at different time points, combined with bacterial swabs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •> 18 years old
- •Cancer of head or neck
排除标准
- 未提供
研究组 & 干预措施
IMRT
Experimental
干预措施: IMRT versus conventional radiotherapy (Procedure)
结局指标
主要结局
Volume of saliva
时间窗: Before, during (week 4) and after radiation (week 2, 3, 6 and 12)
Quality of saliva
时间窗: Before, during (week 4) and after radiation (week 2, 3, 6 and 12)
Oral flora
时间窗: Before, during (week 4) and after radiation (week 2, 3, 6 and 12)
次要结局
未报告次要终点
研究者
研究点 (2)
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