A Study of the Effect on Oro-dental Complications of Intensity Modulated Radiotherapy (IMRT) Versus Conventional Radiotherapy in Patients With Cancer of the Head or Neck
Not Applicable
Completed
- Conditions
- Cancer: Head or Neck
- Interventions
- Procedure: IMRT versus conventional radiotherapy
- Registration Number
- NCT00323466
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
Study to investigate the effect of two types of radiotherapy on saliva: IMRT versus conventional radiotherapy.
In each group, one part will receive normal dental preventive treatment. The other part will use products for treatment of dry mouth (Biotene gamma).
Both anorganic and organic components of the saliva will be studied at different time points, combined with bacterial swabs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 43
Inclusion Criteria
- > 18 years old
- Cancer of head or neck
Exclusion Criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description IMRT IMRT versus conventional radiotherapy -
- Primary Outcome Measures
Name Time Method Volume of saliva Before, during (week 4) and after radiation (week 2, 3, 6 and 12) Quality of saliva Before, during (week 4) and after radiation (week 2, 3, 6 and 12) Oral flora Before, during (week 4) and after radiation (week 2, 3, 6 and 12)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium