ACTRN12612000460808
Completed
Phase 2
In people with knee osteoarthritis, does manual therapy in addition to exercise therapy reduce pain and disability, compared with exercise therapy alone, and do booster sessions enhance the effectiveness compared with no booster sessions.
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversity of Otago
- Enrollment
- 75
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •40 years of age or older
- •Meet the American College of Rheumatology (ACR) clinical criteria for a diagnosis of knee OA. The ACR clinical criteria for knee OA includes knee pain plus 3 of the following 6 criteria:
- •age \> 50 years,
- •morning stiffness of \< 30 minutes,
- •crepitus on active movement,
- •tenderness of the bony margins of the joint,
- •bony enlargement of the joint noted on exam,
- •lack of palpable warmth of the synovium. Based on this criteria, a subject who is less than 50 years but has knee pain and 3 of the other 5 criteria would also be classified as having knee OA.
Exclusion Criteria
- •do not meet the ACR clinical criteria for knee OA,
- •are scheduled for total knee arthroplasty (TKA) surgery,
- •have undergone TJA surgery on any lower extremity joint,
- •exhibit uncontrolled hypertension (i.e. individuals not currently taking medication for hypertension whose systolic blood pressure is greater than 140 mm Hg or diastolic blood pressure greater than 90 mm Hg at rest),
- •have complaints of low back pain or other lower extremity joint pain that affects function at the time of recruitment,
- •have a history of neurological disorders that would affect lower extremity function (stroke, peripheral neuropathy, parkinson's disease, multiple sclerosis, etc.),
- •are women who are pregnant.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Prospective clinical study using X-ray to evaluate fixation of cementless total knee replacement componentsACTRN12609000514202Stryker Australia20
Not yet recruiting
Phase 4
An Assessment of the Effects of a Nutritional Supplement Program on Healthy AgingACTRN12607000613404Mannatech Australia Pty Ltd20
Completed
Not Applicable
Comparison study of two different techniques for knee replacementOsteoarthritis of the kneeMusculoskeletal - OsteoarthritisSurgery - Surgical techniquesACTRN12611000147987Stryker Australia100
Completed
Not Applicable
A study of patient-specific cutting guides for total knee joint replacement.Osteoarthritis of the kneeMusculoskeletal - OsteoarthritisACTRN12610000192088Stryker Australia100
Not yet recruiting
Phase 4
Do people with painful knee osteoarthritis have greater pain sensitivity than similar aged healthy people, and can this pain sensitivity be altered by a 2-week course of the anti-inflammatory Arcoxia?osteoarthritischronic painMusculoskeletal - OsteoarthritisACTRN12609000524291Curtin University of technology80