In people with knee osteoarthritis, does manual therapy in addition to exercise therapy reduce pain and disability, compared with exercise therapy alone, and do booster sessions enhance the effectiveness compared with no booster sessions.

niversity of Otago0 个研究点目标入组 75 人开始时间: 2012年4月24日最近更新: 2020年1月13日

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•40 years of age or older
•Meet the American College of Rheumatology (ACR) clinical criteria for a diagnosis of knee OA. The ACR clinical criteria for knee OA includes knee pain plus 3 of the following 6 criteria:
•age > 50 years,
•morning stiffness of < 30 minutes,
•crepitus on active movement,
•tenderness of the bony margins of the joint,
•bony enlargement of the joint noted on exam,
•lack of palpable warmth of the synovium. Based on this criteria, a subject who is less than 50 years but has knee pain and 3 of the other 5 criteria would also be classified as having knee OA.

•do not meet the ACR clinical criteria for knee OA,
•are scheduled for total knee arthroplasty (TKA) surgery,
•have undergone TJA surgery on any lower extremity joint,
•exhibit uncontrolled hypertension (i.e. individuals not currently taking medication for hypertension whose systolic blood pressure is greater than 140 mm Hg or diastolic blood pressure greater than 90 mm Hg at rest),
•have complaints of low back pain or other lower extremity joint pain that affects function at the time of recruitment,
•have a history of neurological disorders that would affect lower extremity function (stroke, peripheral neuropathy, parkinson's disease, multiple sclerosis, etc.),
•are women who are pregnant.

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