A Comparative Study Of Hyaluronic Acid Gel Vs Intrauterine Device For Prevention Of Intrauterine Adhesions Following Operative Hysteroscopy
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Prevention of intrauterine adhesions (IUAs), with sub-outcomes including the recurrence of adhesions, fertility outcomes, patient discomfort, and satisfaction
研究概览
简要总结
Intrauterine adhesion (IUA) or Asherman’s syndrome, are defined as the replacement of stroma with fibrous tissue, and of the glands with inactive cub-columnar endometrial epithelium. IUAs often occur after damage to the endometrium and its prevalence varies widely by the type intrauterine procedure that causes the damage. IUA is associated with impaired reproductive outcomes following both natural conception and assisted reproduction technology. An ideal treatment for IUAs involves dissecting the adhesions to restore the shape and volume of the uterine cavity, and to prevent adhesion reformations. Hysteroscopic adhesiolysis has become the standard treatment choice for IUAs management. However, potential damage caused by this surgery may lead to an adhesion-prone condition of the endometrium.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 44.00 Year(s)（—）
- 性别
- Female
入选标准
- •Scheduled for operative hysteroscopy (e.g., myomectomy, polypectomy, or endometrial resection) due to intrauterine pathology.
- •Informed consent obtained.
排除标准
- •Women with active pelvic infections, uterine cancer, or other contraindications to hysteroscopic surgery or IUD placement.
- •Women with a history of severe uterine malformations or previous major uterine surgery.
- •Pregnant or breastfeeding women.
结局指标
主要结局
Prevention of intrauterine adhesions (IUAs), with sub-outcomes including the recurrence of adhesions, fertility outcomes, patient discomfort, and satisfaction
时间窗: 1 MONTH
次要结局
未报告次要终点
研究者
Shaikh Muneeba
Jawaharlal Nehru Medical college