NL-OMON32808招募中不适用
ADMA and renal endothelial dysfunction: de effects of ARB and/or statins in hypertensive patients with mild renal insufficiency - ADMA and renal endothelial dysfunction
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 69
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •o Hypertension
- •(Office blood pressure >140 and/or >90 mmHg or ABPM blood pressure:
- •>125 and/or >80 mmHg)
- •o Age: 18-75 jaar
- •o Creatinin clearance of 60-90 mL/min
- •(Cockcroft-Gault formula)
- •o Renal angiography indicated, based on the following criteria:
- •- Refractory hypertension
- •- Accelerating or malignant hypertension
- •- Elevating serum creatinin after an ACE-inhibitor or ARB
- •- Kidney size < 8 cm measured by ultrasound
- •- Unexplained hypokalemia
- •- Abdominal or
- •renal souffle
- •- Manifestations of atherosclerosis
- •- *Flash* oedema
排除标准
- •o Primary kidney diseases or urological complaints
- •o Diabetes Mellitus
- •o Chronic inflammatory diseases
- •o Recent infections (< 3 weeks)
- •o Unilateral or bilateral renal artery stenosis
- •o Fibromuscular dysplasia (FMD)
- •o Contraindication for ARB or statin
- •o Use of > 4 units alcohol a day
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