The Effect of Embryo Culture Under a Continuous CO2 Setting Versus a Sequential CO2 Setting
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- blastulation rate
研究概览
简要总结
The purpose of this study is to determine if embryo culture under a single CO2 setting improves blastocyst formation rate.
详细描述
Following enrollment, patients will undergo ovarian stimulation and oocyte retrieval per routine as previously consented to at the clinic. IVF stimulation protocol will be at the discretion of the patient's individual provider, per routine. Intracytoplasmic Sperm Injection (ICSI) will be performed and embryos will be cultured to the blastocyst stage per routine. There are no changes to the embryology care itself, the only difference within the study is the CO2 level within the incubator pending the patient's randomization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Major Inclusion Criteria for participants:
- •Patients undergoing IVF stimulation cycle with plan for subsequent FET
排除标准
- •for participants:
- •All patients who do not voluntarily give their written consent for participation
- •Male partner with <100,000 total motile spermatozoa per ejaculate (donor sperm is acceptable)
- •Use of surgical procedures to obtain sperm
研究组 & 干预措施
Continuous CO2 Level
embryos will remain in a single incubator set at a continuousCO2 level
干预措施: Continuous CO2 Level (Other)
Sequential CO2 Level
Current standard of care
结局指标
主要结局
blastulation rate
时间窗: approximately one week
the number of zygotes that reach the blastocyst stage
次要结局
未报告次要终点