Diagnostic Values of Lung Ultrasound for Perioperative Atelectasis

Completed

• Conditions: Postoperative Pulmonary Atelectasis

• Registration Number: NCT02355405
• Lead Sponsor: The Third Xiangya Hospital of Central South University

Brief Summary

Lung ultrasound offers a novel, reliable and radiation-free tool for diagnosing perioperative atelectasis and evaluating its severity in adult patients undergoing general anesthesia in the operating room.

Detailed Description

Atelectases occur in up to 90% of patients undergoing general anesthesia and intubation. The aim of the present observational study was designed to further to evaluate the diagnostic performance of lung ultrasound (LUS) in detection of postoperative atelectasis in adult patients undergoing general anesthesia. Results of LUS as the experimental method will be compared to the results of computed tomography (CT) as the reference technique for the detection of atelectasis. The investigators want to confirm former findings of the appearance of perioperative atelectases and to prove that ultrasound is a valid tool for detection of atelectases.

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-01-30
• Study First Submitted QC: 2015-01-30
• Study First Posted: 2015-02-04
• Primary Completion: 2015-03
• Status Verified: 2015-04
• Study Completion: 2015-04
• Last Update Submitted: 2015-04-17
• Last Update Posted: 2015-04-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

1. Aged 18 years and older;
2. American Society of Anesthesiologists (ASA) physical status within class I-III;
3. Scheduled for selective neurosurgical operation with general anesthesia;
4. Need of mechanical ventilation more than 2 hours;

Exclusion Criteria

1. Patients decline to participate;
2. Pregnancy;
3. Previous thoracic procedures (thoracic drain, thoracotomy, thoracoscopy);
4. A history of pulmonary diseases within last two weeks with abnormal manifestation of lung CT (pulmonary parenchyma or/and interstitial lesions );
5. Pneumothorax or subcutaneous emphysema during peri-operation;
6. Patients with a body mass index (BMI) more than 30 kg/m2;
7. Emergency operation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between manifestations of atelectasis in lung ultrasound and in thoracic computed tomography.	From 5 minutes before induction of anesthesia to 1 hour after the surgery	Measurements of lung ultrasound are performed before induction of anesthesia and immediately after finishing the surgery. Lung CTs are performed the day before surgery and within 1 hour after surgery. Outcome measure: comparison of atelectases by lung ultrasound (experimental method) versus by computed tomography (standard method)

Trial Locations

Locations (2)

Xiangya Hospital of Central South University; 🇨🇳 Changsha, Hunan, China

The Third Xiangya Hospital of Central South University; 🇨🇳 Changsha, Hunan, China