The effect of zinc supplementation on prevention of preterm premature rupture of the membranes

Phase 2

• Conditions: Preterm premature rupture of membranes.; Premature rupture of membranes

• Registration Number: IRCT201311296709N14
• Lead Sponsor: Research Deputy of Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 108

Inclusion Criteria

the history of preterm premature rupture of the membranes at least once in previous pregnancies; singleton pregnancy; normal fetus and amniotic fluid; maternal age 18 years and above; gestational age between 16 and 20 weeks of pregnancy; healthy women without underlying medical condition (cardiac, pulmonary, gastrointestinal, diabetes, epilepsy, hypertension, etc); willingness to participate in the study. Exclusion criteria: the uncertain status of the embryo (abnormal non stress test ); any congenital anomalies of the fetus; any complications of pregnancy (history of preeclampsia and current chronic hypertension, bleeding and threatened abortion, nausea and vomiting, etc ); having an addiction to drugs and alcohol; taking multivitamin mineral supplementation during pregnancy; severe vaginal infection (with discharge, itching, swelling, erythema, and foul-smelling discharge)

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Preterm premature rupture of the membranes. Timepoint: 20 to 37 weeks. Method of measurement: View sterile Speculum and Nitrazine test.

Secondary Outcome Measures

Name	Time	Method
Gestational age. Timepoint: Delivery time. Method of measurement: By last menstrual period date and sonography.