The Impact of Various Storage Techniques on Platelet Function
试验速览
- 阶段
- 2 期
- 状态
- 撤回
- 主要终点
- Change in platelet function
研究概览
简要总结
Platelet function will be tested in individuals on antiplatelet medications to determine the optimal storage methodology.
详细描述
Subjects will undergo administration of antiplatelet drugs and then will receive platelets stored in a variety of methods. Platelet function will be measured serially.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
盲法说明
the assesor of platelet function and the PI will be blinded to group.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normal subjects
排除标准
- •Pre existing antiplatelet drugs
研究组 & 干预措施
Control (Placebo)
Subjects will receive infusion of placebo (saline).
干预措施: Placebo (Biological)
Platelet storage routine
Subjects will receive infusion of platelets stored by routine method.
干预措施: Infusion of Platelets (Biological)
Platelet storage experimental
Subjects will receive infusion of platelets stored by a novel methodology.
干预措施: Infusion of Platelets (Biological)
结局指标
主要结局
Change in platelet function
时间窗: 1 hour post-transfusion
Frozen platelets will result in improvement in platelet function after transfusion.
次要结局
未报告次要终点