Long-term Efficacy and Safety Research of Left Bundle Branch Pacing
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Atrioventricular Block
- Sponsor
- Linyi People's Hospital
- Enrollment
- 136
- Locations
- 1
- Primary Endpoint
- Change from Baseline in left ventricular ejection fraction at 3 years
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Patients with successful left bundle branch pacing in our center were included in this study from April 2018 to December 2019. Baseline data was collected, and pacing parameters, ECG and echocardiographic results were analyzed during 3 years follow-up. According to whether or not a potential was recorded and the specific potential characteristics at implantation, the patients were divided into 3 groups: left bundle branch potential group; Purkinje potential group; and no-potential group. During the 3 years follow-up, the investigators collected the ECG、UCG and pacemaker parameters to analyze.
Detailed Description
A total of 136 patients with a high percentage of ventricular pacing and successful left bundle branch pacing were included in this study from April 2018 to December 2019. Baseline data was collected, and pacing parameters, ECG and echocardiographic results were analyzed during 3 years follow-up. According to whether or not a potential was recorded and the specific potential characteristics at implantation, the patients were divided into 3 groups: left bundle branch potential group (L group) 31.6%; Purkinje potential group (P group) 10.3%; and no-potential group (N group) 58.1%. During the 3 years follow-up, the investigators collected the ECG、UCG and pacemaker parameters to analyze.
Investigators
Xinhua Li
Deputy director of Cardiology
Linyi People's Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients who were predicted to require a high percentage of ventricular pacing in our center were enrolled in this study
Exclusion Criteria
- •Low rate of pacing, and loss to follow-up
Outcomes
Primary Outcomes
Change from Baseline in left ventricular ejection fraction at 3 years
Time Frame: Baseline and 3 years
Left ventricular ejection fraction (%)
Change from Baseline in left ventricular end diastolic diameter at 3 years
Time Frame: Baseline and 3 years
Left ventricular end diastolic diameter (ms)
Change from Baseline in left atrium diameter at 3 years
Time Frame: Baseline and 3 years
Echocardiography is measured by a professional using an ultrasound machine, record the following results: left atrium diameter (ms)
Change from Baseline in pulmonary artery systolic pressure at 3 years
Time Frame: Baseline and 3 years
Pulmonary artery systolic pressure (mmHg)
Secondary Outcomes
- Change from Baseline in threshold at 3 years(Baseline and 3 years)
- Change from Baseline in impedance at 3 years(Baseline and 3 years)