Long-term Efficacy and Safety Research of Left Bundle Branch Pacing
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 136
- 试验地点
- 1
- 主要终点
- Change from Baseline in left ventricular ejection fraction at 3 years
研究概览
简要总结
Patients with successful left bundle branch pacing in our center were included in this study from April 2018 to December 2019. Baseline data was collected, and pacing parameters, ECG and echocardiographic results were analyzed during 3 years follow-up. According to whether or not a potential was recorded and the specific potential characteristics at implantation, the patients were divided into 3 groups: left bundle branch potential group; Purkinje potential group; and no-potential group. During the 3 years follow-up, the investigators collected the ECG、UCG and pacemaker parameters to analyze.
详细描述
A total of 136 patients with a high percentage of ventricular pacing and successful left bundle branch pacing were included in this study from April 2018 to December 2019. Baseline data was collected, and pacing parameters, ECG and echocardiographic results were analyzed during 3 years follow-up. According to whether or not a potential was recorded and the specific potential characteristics at implantation, the patients were divided into 3 groups: left bundle branch potential group (L group) 31.6%; Purkinje potential group (P group) 10.3%; and no-potential group (N group) 58.1%. During the 3 years follow-up, the investigators collected the ECG、UCG and pacemaker parameters to analyze.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who were predicted to require a high percentage of ventricular pacing in our center were enrolled in this study
排除标准
- •Low rate of pacing, and loss to follow-up
结局指标
主要结局
Change from Baseline in left ventricular ejection fraction at 3 years
时间窗: Baseline and 3 years
Left ventricular ejection fraction (%)
Change from Baseline in left ventricular end diastolic diameter at 3 years
时间窗: Baseline and 3 years
Left ventricular end diastolic diameter (ms)
Change from Baseline in left atrium diameter at 3 years
时间窗: Baseline and 3 years
Echocardiography is measured by a professional using an ultrasound machine, record the following results: left atrium diameter (ms)
Change from Baseline in pulmonary artery systolic pressure at 3 years
时间窗: Baseline and 3 years
Pulmonary artery systolic pressure (mmHg)
次要结局
- Change from Baseline in threshold at 3 years(Baseline and 3 years)
- Change from Baseline in impedance at 3 years(Baseline and 3 years)
研究者
Xinhua Li
Deputy director of Cardiology
Linyi People's Hospital