The Relative Effects of Olmesartan Medoxomil, Irbesartan and Valsartan on the Activity of the Blood Pressure Control System in Healthy Subjects

Phase 4

Completed

• Conditions: Healthy

• Registration Number: NCT00185055
• Lead Sponsor: Daiichi Sankyo

Brief Summary

To assess the effects of 3 blood pressure drugs, called angiotensin receptor blockers, on the blood pressure control systems in healthy subjects.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-11
• Study Completion: 2005-02
• Status Verified: 2005-09
• Study First Submitted: 2005-09-09
• Study First Submitted QC: 2005-09-15
• Last Update Submitted: 2005-09-15
• Study First Posted: 2005-09-16
• Last Update Posted: 2005-09-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Men and women between the ages of 18 to 65
• In good health

Exclusion Criteria

• Any serious health problems
• Positive test for HIV, Hepatitis B and C
• History of drug and alcohol abuse

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
To characterize the plasma renin activity (PRA) and urinary aldosterone response patterns to single doses of olmesartan medoxomil, irbesartan, and valsartan compared to placebo in normal volunteers.