The Diagnostic Performance of Tilt Test in Athletes

Not Applicable

Completed

• Conditions: Syncope
• Interventions: Other: Passive tilt test

• Registration Number: NCT02316860
• Lead Sponsor: Aristotle University Of Thessaloniki

Brief Summary

In the present study the investigators evaluate the sensitivity and specificity of passive tilt test in athletes, as well as their haemodynamic responses and autonomic nervous system activity during head-up tilt. Moreover, the investigators try to apply a novel algorithm for the improvement of diagnostic yield of tilt test in athletes.

Detailed Description

We examine athletes with a history of reflex syncope and athletes without history of reflex syncope.All subjects undergo a tilt test, for the evaluation of haemodynamics, heart rate variability (HRV) and baroreflex sensitivity.

Study Timeline

• Study Start: 2014-10
• Primary Completion: 2014-12
• Study Completion: 2014-12
• Study First Submitted: 2014-12-06
• Study First Submitted QC: 2014-12-11
• Study First Posted: 2014-12-15
• Status Verified: 2017-10
• Last Update Submitted: 2017-10-25
• Last Update Posted: 2017-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• 14-40 years old,
• more than 5 years of exercise training experience and competition at a regional level at different sports

Exclusion Criteria

• smoking,
• recent alcohol consumption,
• presence of any chronic disease and use of drugs

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
History of reflex syncope	Passive tilt test	Passive tilt test in athletes with a history of reflex syncope
No history of reflex syncope	Passive tilt test	Passive tilt test in athletes without history of reflex syncope

Primary Outcome Measures

Name	Time	Method
sensitivity and specificity of tilt test in athletes as measured by the occurence of syncope/presyncope during tilt test	30 min	sensitivity = number of subjects with syncope/presyncope during tilt test/ number of subjects with a history of reflex syncope, specificity = number of subjects without syncope/presyncope during tilt test/ number of subjects without history of reflex syncope

Secondary Outcome Measures

Name	Time	Method
Parameters of baroreflex sensitivity during tilt test	30 min	We investigate whether the mean values of parameters of baroreflex sensitivity during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope
Parameters of haemodynamics during tilt test	30 min	We investigate whether the mean values of parameters of haemodynamics during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope
Parameters of heart rate variability during tilt test	30 min	We investigate whether the mean values of parameters of heart rate variability during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope

Trial Locations

Locations (1)

Laboratory of Sports Medicine, Sports Medicine Division, Aristotle University of Thessaloniki, Thessaloniki, Greece; 🇬🇷 Thessaloniki, Greece