Sarcopenia in Axial and Peripheral Spondyloarthropathies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 106
- 试验地点
- 2
- 主要终点
- Walking speed
研究概览
简要总结
Spondylarthropathies (SpA) are among the most common chronic inflammatory rheumatisms in adults, responsible for a muscular loss or sarcopenia which can be very disabling, not much documented in the literature, and not yet studied in France. In addition, sarcopenia is associated with decreased physical activity and increased risk of falls and fractures. A better characterization of the determinants of this muscular loss will allow to better detect and take care of it.
The aim is to conduct the first French study on the prevalence and severity of sarcopenia in patients with spondyloarthropathies and to study the variables that may be associated with it. Finally, we propose to evaluate obesity related to sarcopenia in these patients and compare them to cases matched for age and sex (from OFELY / STRAMBO cohorts, Lyon, FRANCE).
This is a prospective interventional and monocentric study with minimal risks and constraints: patients will be included for one day for an evaluation of their sarcopenia by measuring their muscle strength, physical performance and body composition and recording of their socio-demographic and disease characteristics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women, 18 to 80 years old
- •Hospitalized or attending the rheumatology department for spondyloarthopathy.
排除标准
- •no signed consent
- •Immobilization for a period of more than 15 days during the last 3 months
- •pregnant or breastfeeding woman
- •Not affiliated to the national healthcare insurance
- •difficulty in understanding French
- •psychiatric disorder
结局指标
主要结局
Walking speed
时间窗: At day 1
Walking speed is a physical performance outcome, that is the second outcome to evaluate sarcopenia
Muscular mass
时间窗: Up to 4 month after inclusion
Muscular mass is the third outcome to evaluate sarcopenia and will be assessed using DXA
Muscular strength
时间窗: At day 1
Muscular strength is the first outcome to evaluate sarcopenia
次要结局
- Alcohol consumption(At day 1)
- Time of sport practice per month(At day 1)
- Physical activity rate in work(At day 1)
- Average walking time in a week(At day 1)
- Tobacco consumption(At day 1)
- Score at the SARQOL questionnaire(At day 1)