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Clinical Trials/NCT04178720
NCT04178720
Completed
Not Applicable

Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens

Alcon Research1 site in 1 country119 target enrollmentJanuary 28, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Refractive Errors
Sponsor
Alcon Research
Enrollment
119
Locations
1
Primary Endpoint
Distance VA (logMAR) With Study Lenses - Completed Eyes
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The purpose of this clinical study is to evaluate the safety and effectiveness of an investigational soft contact lens compared to a commercially available soft contact lens when worn for daily wear and replaced monthly.

Detailed Description

Subjects are expected to attend 6 study visits. The expected duration of study lens exposure is approximately 3 months.

Registry
clinicaltrials.gov
Start Date
January 28, 2020
End Date
June 10, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Successful wear of spherical daily wear frequent replacement soft contact lenses for distance correction in both eyes during the past 3 months for a minimum of 5 days per week and 8 hours per day.
  • Manifest cylinder equal to or less than 0.75 diopter (D) in each eye.
  • Other protocol-specified inclusion criteria may apply.

Exclusion Criteria

  • Wearing habitual contact lenses in an extended wear modality (routinely sleeping in lenses for at least 1 night per week) over the last 3 months prior to enrollment.
  • Habitually wearing Biofinity contact lenses.
  • Monovision contact lens wearers.
  • Other protocol-specified exclusion criteria may apply.

Outcomes

Primary Outcomes

Distance VA (logMAR) With Study Lenses - Completed Eyes

Time Frame: Dispense, Week 1 follow-up, Week 2 follow-up, Month 1 follow-up, Month 2 follow-up, Month 3 follow-up (at least 4 hours after lens insertion at each follow-up assessment visit)

Visual acuity (VA) was assessed for each eye individually with study lenses in place at a distance of 6 meters using a letter chart. VA was collected in Snellen and converted to logarithm minimum angle of resolution (logMAR). A logMAR value of 0 equates to 20/20 Snellen visual acuity (normal distance eyesight), with a lower logMAR value indicating better visual acuity. No formal hypothesis testing was planned.

Distance VA (logMAR) With Study Lenses - Discontinued Eyes

Time Frame: Dispense, Week 1 follow-up, Week 2 follow-up, Month 1 follow-up

Visual acuity (VA) was assessed for each eye individually with study lenses in place at a distance of 6 meters using a letter chart. VA was collected in Snellen and converted to logarithm minimum angle of resolution (logMAR). A logMAR value of 0 equates to 20/20 Snellen visual acuity (normal distance eyesight), with a lower logMAR value indicating better visual acuity. No formal hypothesis testing was planned.

Study Sites (1)

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