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Clinical Trials/NCT05211739
NCT05211739
Completed
Not Applicable

Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens

Alcon Research7 sites in 1 country76 target enrollmentFebruary 15, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Refractive Errors
Sponsor
Alcon Research
Enrollment
76
Locations
7
Primary Endpoint
Distance Visual Acuity (VA) With Study Lenses
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this clinical study is to assess the clinical performance of an investigational toric soft contact lens compared to a commercially available toric contact lens in a crossover dispense trial when worn in a daily wear modality for 30 days, each study lens type.

Detailed Description

Subjects will be randomized to 1 of 2 crossover wear sequences. Subjects will be expected to attend 5 office visits, for a total individual duration of participation in the study of approximately 60 days.

Registry
clinicaltrials.gov
Start Date
February 15, 2022
End Date
June 23, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Successful wearers of weekly/monthly toric soft contact lenses in both eyes for a minimum of 5 days per week and 10 hours per day during the past 3 months;
  • Best corrected distance visual acuity (as determined by manifest refraction at screening) better than or equal to 20/25 Snellen in each eye.
  • Able to wear contact lenses within the range of available sphere \& cylinder power and axes.
  • Other protocol-defined inclusion criteria may apply.

Exclusion Criteria

  • Daily disposable contact lens wearers.
  • Monovision and multifocal contact lens wearers.
  • Habitual Biofinity Toric/Biofinity Toric XR contact lens wearers in the past 3 months prior to consent.
  • Other protocol-defined exclusion criteria may apply.

Outcomes

Primary Outcomes

Distance Visual Acuity (VA) With Study Lenses

Time Frame: Day 1 and Day 30, each wear period (approximately 30 days)

Visual acuity (VA) was collected for each eye individually with study lenses in place using a letter chart. VA was measured in logarithm minimum angle of resolution (logMAR). A logMAR value of 0 equates to 20/20 Snellen visual acuity (normal distance eyesight), with a lower logMAR value indicating better visual acuity. No inferences were pre-specified for the primary effectiveness endpoint; therefore, no hypothesis testing was performed.

Study Sites (7)

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