The chronic effects of dietary fibre on metabolic syndrome risk factors in overweight and obese individuals.

Not Applicable

Completed

• Conditions: Metabolic risk factors in overweight and obese individuals; Diet and Nutrition - Obesity; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12609000540213
• Lead Sponsor: Curtin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-07-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

Body Mass Index (BMI) between 25 40kg/m2
Healthy
Not on regular medications
Non-smoker
No major diseases or disorders

Exclusion Criteria

Smoking
Medications - lipid lowering, steroids, warfarin, blood pressure
Diabetes
Thyroid dysfunction
Cardiovascular events in previous 6 months
Psychological unsuitability
Major systemic diseases
GI problems
Liver disease
Kidney dysfunction

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improved fasting blood lipid, lipoprotein profile, glucose and insulin response was measured by blood analysis.[Fasting blood samples taken at 0, 6 and 12 weeks. Analysis of lipids, lipoproteins, glucose and lipids were conducted using different biochemical kits.];Improved blood pressure after 12 weeks. Blood pressure will be measured by research assistant using Systolic blood pressure (SBP) and diastolic blood pressure (DBP) measured on the left arm of participants with an automated sphygmomanometer (Dinamap ProCare). Subjects will be rested in a supine position before and during measurements.[Measured at 0, 6 and 12 weeks]

Secondary Outcome Measures

Name	Time	Method
Improved vascular endothelium function via Sphygmocor pulse wave analysis (PWA)[Measured at 0, 6 and 12 weeks]