Evaluation of metabolic bone disease and fracture prevalence in patients with Crohn’s disease

Recruiting

• Conditions: K50.9; M82; Crohn disease, unspecified; Osteoporosis in diseases classified elsewhere

• Registration Number: DRKS00013028
• Lead Sponsor: udwig Boltzmann Institut für Osteologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-09-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 218

Inclusion Criteria

Patients with Crohn´s disease at least 18 years old

Control subjects will be recruited from a preventive medical examination program.

Exclusion Criteria

• Critically or terminally ill patients.
• Unable to comply with study protocol.
• Pregnancy (positive urine pregnancy test)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bone Mineral Density by DXA (only in patients with Crohn's disease)

Secondary Outcome Measures

Name	Time	Method
Questionnaires (Age, weight, height,CD diagnosis date and history, Gender, Current and preceding medications, Comorbidities, Fracture history in 1st degree relatives, Smoking and Alcohol status, Number of flare-ups requiring a visit to the physician and/or corticosteroid use during the preceding year, Lifestyle factors including, history of fractures, BMI, and dietary factors, OSTEO-CHECK and IBDQ-D questionnaire), CDAI (Crohn's Disease Activity Index), lab parameters (biochemistry profile, Malabsorbtion testing, blood count,<br>Bone metabolism relevant hormones and vitamins, inflammatory parameters, Stool analysis, Bone metabolism markers)