Can nitric oxide donors treatment improve pregnancy outcome in patients with antiphospholipid syndrome?

Completed

• Conditions: Antiphospholipid syndrome; recurrent abortion; premature labor; Reproductive Health and Childbirth - Abortion; Inflammatory and Immune System - Autoimmune diseases

• Registration Number: ACTRN12614000586617
• Lead Sponsor: Benha university hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-06-02
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 34

Inclusion Criteria

Patients with recurrent abortion or premature labor with preclampsia due to antiphospholipid syndrome

Exclusion Criteria

Recurrent abortion or premature labor due to causes other than antiphospholipid syndrome as uterine anomalies, cervical incompetence and chronic diseases

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of full term live birth[End of pregnancy at 37-40 weeks gestation ];Compliance of patients to treatment in both groups was assessed by drug tablet return and satisfaction with treatment in both groups was assessed using structured interviews [End of pregnancy];Incidence of abortion [termination of pregnancy before 20 weeks gestation]

Secondary Outcome Measures

Name	Time	Method
Doppler ultrasound measurement of uterine artery resistance and pulsation indices at 24 weeks after treatment compared to before treatment[At 24 weeks gestation]