The efficacy of progestin primed ovarian stimulation (PPOS) during controlled ovarian stimulation(COS) for patients with endometriosis - PPOS for patients with endometriosis

Kamiya Ladies Clinic0 sites150 target enrollmentFebruary 5, 2018

Conditionsinfertility

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: infertility
Sponsor: Kamiya Ladies Clinic
Enrollment: 150
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

During this study, no premature LH surge was detected. A smaller number of oocytes were retrieved in the dienogest(DNG) group than in the dydrogesterone(DYG) group (6.18 vs. 9.85); however, the rate of mature oocytes was significantly higher in the DNG group than in the DYG group (89.1% vs. 78.9%). The fertilization rate was comparable between two groups. Therefore, patients taking DNG for PPOS can continue endometriosis treatment and obtain good-quality embryos during COH.

Registry

who.int

Start Date

February 5, 2018

End Date

December 31, 2021

Last Updated

2 years ago

Study Type

Interventional

Sex

Female

Investigators

Sponsor

Kamiya Ladies Clinic

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•1\) Patients who documented cycles with no oocyte retrieved, any contraindications to ovarian stimulation treatment and 2\) patients who has contraindication to DNG, GnRHa, EP, FSH, HMG, HCG 3\) Patients who is judged to be inappropriate for this study by the doctor