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The efficacy of furosemide in reducing methotrexate toxicity in patients suffering from Acute lymphoblastic leukemia

Phase 2
Conditions
Health Condition 1: C910- Acute lymphoblastic leukemia [ALL]
Registration Number
CTRI/2024/02/062267
Lead Sponsor
All India Institute of medical sciencesPatna
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Children diagnosed to have acute lymphoblastic leukemia on high dose methotrexate therapy.

Exclusion Criteria

children with chronic kidney disease,Chronic liver disease

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
serum methotrexate levelsTimepoint: 48 hours after starting high dose methotrexate Therapy.
Secondary Outcome Measures
NameTimeMethod
hemoglobin levels,ANC levels ,Liver enzymes, urea and creatinineTimepoint: 48 hrs
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