Concomitant presence of celiac disease in patients with type 1 diabetes mellitus; investigation of the microvascular functio

Completed

• Conditions: diabetic; Gluten sensitive enteropathie; 10047066

• Registration Number: NL-OMON37809
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- Men and women older than 18 years of age
- Patients diagnosed with type 1 diabetes
- Patients with concomitant celiac disease for at least one year
- Informed consent
- Duration of T1DM between 9 and 14 years

Exclusion Criteria

- A psychiatric, addictive or any disorder that compromises the patient to understand the study content and to give written informed consent for participation in this study.
- A history of Raynaud's disease, scleroderma or concurrent infection

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>3 primary study parameters which determine the microvascular function:<br /><br>- Capillary recruitment after post-occlusive hyperaemia<br /><br>- Acetylcholine mediated vasodilatation<br /><br>- Accumulation of Advanced Glycation End product in the skin</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>