COMPARISON OF TWO DOSES OF CARBETOCIN WITH OXYTOCIN FOR THE PREVENTION OF POSTPARTUM BLEEDING
Not Applicable
Recruiting
- Conditions
- Postpartum haemorrhage
- Registration Number
- PACTR202204640411588
- Lead Sponsor
- Rasheedat Balogun
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 321
Inclusion Criteria
Healthy pregnant women at term
Exclusion Criteria
Women with history of, or being treated for bleeding disorder
Women with intrauterine fetal demise
Women with antepartum haemorrhage
Women requiring general anaesthesia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Uterine contractility by palpation (as recommended by WHO)13, at two and five minutes by the attending accoucheur after intravenous administration of the study drug. This is because of the onset of action of carbetocin at 2 minutes with contractions lasting for about 6 minutes following its administration2.<br>- Estimated blood loss after intravenous administration of the study drug.
- Secondary Outcome Measures
Name Time Method -The use of additional uterotonic agents, <br>-The need for blood transfusion.<br>-The need for additional surgical interventions such as hysterectomy <br>-The occurrence of side effects (hypo/hypertension, brady/tachycardia, nausea/vomiting, flushing, headache, others) following the administration of the study drug.