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Clinical Trials/NCT05186272
NCT05186272
Active, not recruiting
Phase 3

mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression

Kaiser Permanente1 site in 1 country600 target enrollmentJune 14, 2022

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Post Partum Depression
Sponsor
Kaiser Permanente
Enrollment
600
Locations
1
Primary Endpoint
Patient Health Questionnaire-9
Status
Active, not recruiting
Last Updated
9 months ago

Overview

Brief Summary

Postpartum depression (PPD) is associated with significant health consequences for mothers and children, and the current COVID-19 pandemic has had a major impact on the mental health of particularly vulnerable populations including pregnant Black and Latina women. There is an urgent need for evidence-based, accessible, and scalable mental health care options for these high-risk, vulnerable women. This study aims to: (a) compare the effectiveness of two digitally-delivered self-paced stress reduction programs in pregnant Black and Latina women at increased risk of PPD; and (b) examine barriers and facilitators to implementation within a large healthcare system.

Registry
clinicaltrials.gov
Start Date
June 14, 2022
End Date
December 1, 2025
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age ≥18 years
  • Current Kaiser Permanente Permanente Northern California (KPNC) member
  • Pregnant woman receiving prenatal care at KPNC
  • Gestational age \<30 weeks
  • Singleton pregnancy
  • Self-identify as Black and/or Latina
  • Moderate to moderately severe depressive symptoms (PHQ-9 score between 10 and 19) and no indication of suicidality
  • Owns a device with internet access
  • English- or Spanish-speaking

Exclusion Criteria

  • Regular stress reduction practice with a mindfulness component (e.g., meditation or yoga more than twice a week)
  • Acting as gestational carrier/surrogate

Outcomes

Primary Outcomes

Patient Health Questionnaire-9

Time Frame: 7 weeks postpartum

Depression scale; total score range of 0-27; higher scores indicate higher depression.

Secondary Outcomes

  • Generalized Anxiety Disorder 7-item scale(7 weeks postpartum)
  • Promis Sleep Disturbance - Short Form 6a(7 weeks postpartum)
  • Perceived Stress Scale(7 weeks postpartum)

Study Sites (1)

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