Perinatal Depression: Dyadic-IPT to Improve Health of Mother and Baby
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Depressive Disorder, Major
- Sponsor
- Washington University School of Medicine
- Enrollment
- 42
- Locations
- 1
- Primary Endpoint
- Change in Edinburgh Depression Scale From Baseline
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Perinatal depression is a major public health problem, affecting 15% of women during pregnancy through the postpartum period, with adverse consequences for the mother, the fetus, the infant, and the family. Despite increasing evidence of the importance of this critical risk interval, little research has investigated the effects of depression treatment during pregnancy on infant outcomes. The purpose of this study is to test the feasibility, acceptability, and effectiveness of a new intervention, Interpersonal psychotherapy for the mother-infant dyad (IPT-Dyad). This intervention begins during pregnancy and continues with the mother and infant until one year postpartum. The investigators hypothesize that IPT-Dyad will be better than treatment as usual in reducing depressive symptoms, improving psychosocial functioning,increasing parenting self-efficacy, improving infant emotional development, and enhancing mother-infant relationship quality.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Pregnant women
- •18 years and older
- •between 12 and 30 weeks gestation
- •Score greater than or equal to 13 on Edinburgh Depression Scale
- •Structured Clinical Interview (SCID-IV) diagnosis of Major Depressive Disorder, dysthymia, or Depressive Disorder, Not otherwise Specified
- •English Speaking
Exclusion Criteria
- •Substance abuse or dependence in past 3 months
- •Active suicidal or homicidal ideation
- •Bipolar disorder, psychotic disorder
- •unstable medical condition or other medical/obstetrical complication
- •Evidence of severe intimate partner violence
- •Ongoing psychosocial or pharmacotherapy for depression
Outcomes
Primary Outcomes
Change in Edinburgh Depression Scale From Baseline
Time Frame: Change from baseline at End of pregnancy (between 37-39 weeks gestation); change from baseline at 3 months postpartum; change from baseline at 6 months postpartum; change from baseline at 9 months postpartum; change from baseline at 12 months postpartum
Edinburgh Postnatal Depression Scale, a 10-item scale of depression severity, scores range from 0 to 30 with higher scores indicating worse outcome.