Study of Apatyakar Ghrita in Ksheena Shukra

Completed

• Conditions: Oligospermia. Ayurveda Condition: SUKRAKSHAYAH,

• Registration Number: CTRI/2022/09/046068
• Lead Sponsor: Government Ayurvedic College Chaukaghat Varanasi

Brief Summary

Interventional Study

Patient suffering from oligozoospermia will be selected from OPD of Govt. Ayurvedic College & Hospital, Chaukaghat, Varanasi



Total Patient = 60



Treatment Plan :-



GROUP A – 30 patients of Group A will be treated by Apatyakar Ghrita prepared with Naveena Ghrita.



GROUP B – 30 patients of Group B will be treated by Apatyakar Ghrita prepared with Purana Ghrita.



Follow up - 15 days for 3 Month



Result -

Under this clinical study, min 60 patient of oligozoospermia was registered but only 50 patient completed the trial. 26 patient were given Apatykar ghrita prepared from Naveena ghrita and 24 patient was given Apatyakar ghrita prepared from Purana ghrita. This medication improve the quality of sperm in terms of Sperm count, sperm motility, and sperm morphology. The overall effect in group A was 60.46% where as in group B was 59.4% Effect of therapy was approximately same. Hence differences in the effect of Apatyakar ghrita prepared from Naveena ghrita and Apatyakar ghrita prepared from Purana ghrita were statistically non-significant.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-10
• Study Completion: 2023-06-30
• Last Update Posted: 2023-09-23

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

• Male partner of a couple presenting for infertility.
• Moderate abnormalities of semen parameters (Mean sperm density <20 million, but ≥ 3 million/ml), and/or motility < 50%, and/or < 4% abnormal morphology on at least two separate occasions as per WHO Criteria.

Exclusion Criteria

• Subjects were under treatment of gonadotropin, anabolic steroid, chemotherapeutic drugs, or nonsteroidal anti-inflammatory drugs.
• Vasectomy reversal.
• Regular use of tobacco products.
• Inability or unwillingness to participate in evaluations required by the study.
• Subjects associated with systemic illness such as Diabetes or Hypertension.
• Subjects had heat, chemicals, radioactive material, or toxic contact history within a year.
• If any adverse effect is observed in patient after consuming Apatyakar Ghrita.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in Sperm Count	90 Days

Secondary Outcome Measures

Name	Time	Method
Enhance the strenght and complexion of body.	Improve Routine Activity

Trial Locations

Locations (1)

Government Ayurvedic college & Hospital; 🇮🇳 Varanasi, UTTAR PRADESH, India

Government Ayurvedic college & Hospital

🇮🇳Varanasi, UTTAR PRADESH, India

Dr Gaurav Kumar Singh

Principal investigator

8006447666

gauravnitin05@gmail.com