Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma

Not Applicable

• Conditions: Ocular Surface Disease; Glaucoma
• Interventions: Drug: sodium hyaluronate; Drug: hydroxypropylmethylcellulose

• Registration Number: NCT01284439
• Lead Sponsor: Mahidol University

Brief Summary

To study effect of hydroxypropylmethylcellulose 0.3% and sodium hyaluronate 0.18% in the treatment of ocular surface disease in glaucoma patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-01
• Study Start: 2011-01
• Study First Submitted: 2011-01-25
• Study First Submitted QC: 2011-01-26
• Last Update Submitted: 2011-01-26
• Study First Posted: 2011-01-27
• Last Update Posted: 2011-01-27
• Primary Completion: 2012-01
• Study Completion: 2012-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• OSDI > or equal 20 and eye lid inflammation , meibomian gland inflammation,conjunctival injection,follicle at tarsus , positive corneal staining , tear break up time less than 8 seconds , tear volume less than 5.5 mm.

Exclusion Criteria

• Age below 18 yo
• Active infectious corneal disease
• Post penetrating keratoplasty or glaucoma drainage device
• Known allergy to medication
• Lactation , Pregnant

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
TearB	sodium hyaluronate	-
TearA	hydroxypropylmethylcellulose	-

Primary Outcome Measures

Name	Time	Method
Ocular surface index score	1 month

Secondary Outcome Measures

Name	Time	Method
Eye lid inflammation, corneal staining score, tear break up time and tear volume	1 month

Trial Locations

Locations (1)

Department of Ophthalmology , Siriraj Hospital; 🇹🇭 Bangkok, Thailand