Comparison of prophylactic effect of single-dose and continuous-dose antibiotics on urinary tract infections (UTI) following transurethral lithotripsy (TUL) and stenting

Phase 2

Recruiting

Conditions: Post-operative urinary tract infection.
Infection and inflammatory reaction due to urinary catheter
T83.51

Registration Number: IRCT20220213054009N1

Lead Sponsor: rology Research Center, Guilan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 90

Inclusion Criteria

Have a sterile urine culture before stent placement

Exclusion Criteria

Fever
Use of antibiotics during the 2 weeks before the stenting operation
Purulent discharge during TUL
History or treatment of obstructive symptoms
Chronic bacterial prostatitis
Chronic pelvic pain syndrome
Prostate cancer
Chronic ureteral obstruction
Obstruction due to malignancy
Iatrogenic trauma
Conditions prone to bleeding
History of bladder cancer
Recurrent urinary tract infections
Irritable bladder syndrome
History of mental or neurological disease
Taking alpha-blockers and anticholinergics, painkillers, or other medications that may interfere with the symptoms of ureteral stent
Pregnancy

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rinary tract infection after inserting the stent. Timepoint: The mean duration of stent indwelling time and before removing the stent. Method of measurement: Urine culture and urinalysis.;Fever. Timepoint: During the stent indwelling time. Method of measurement: Interview and physical exam.;Hematuria. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Dysuria. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Frequency. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Nocturia. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Flank pain. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.

Secondary Outcome Measures