A study to determine the effect of post-infusion cooling time in the high dose FEC-regimen.
Completed
- Conditions
- breast cancerFEC high chemotherapyalopeciascalp cooling
- Registration Number
- NL-OMON25604
- Lead Sponsor
- S. de BieMedisch Centrum Almaars.m.de.bie@mca.nl072-5484444
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 130
Inclusion Criteria
1. Intravenous administered FEC-regimen with an epirubicine dose of 90 mg/m2 or more at 3-weekly intervals;
2. Age 18 years or more;
3. Written informed consent.
Exclusion Criteria
1. Boldness before the start of the study; 2. Hematological malignancies with generalized haematogenic metastases and if in those conditions chemotherapy is given with a curative intent;
3. Clinical signs of sclap metastases.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The need to wear a wig or other head covering
- Secondary Outcome Measures
Name Time Method 1. Acceptability of scalp cooling;<br>2. Relation of the efficacy of scalp cooling with prior chemotherapy/radiotherapy or hormonal treatment, liver- or kidney function disorder and type of hair;<br>3. Quality Of Life during chemotherapy.