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The effect of metformin on treatment of squamous cell carcinoma of neck

Phase 2
Conditions
Malignant neoplasm of larynx.
Malignant neoplasm of larynx, unspecified
C32.9
Registration Number
IRCT20191203045594N1
Lead Sponsor
Shiraz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
25
Inclusion Criteria

All patients with biopsy-proven squamous cell carcinoma of hypopharynx, nasopharynx, and larynx

Exclusion Criteria

All patients with distant metastasis
Hypersensitivity to metformin

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The complete response. Timepoint: 12 weeks after the intervention. Method of measurement: Spiral CT scan.;Toxicity. Timepoint: Weekly. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE).
Secondary Outcome Measures
NameTimeMethod
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