The effect of metformin on treatment of squamous cell carcinoma of neck
Phase 2
- Conditions
- Malignant neoplasm of larynx.Malignant neoplasm of larynx, unspecifiedC32.9
- Registration Number
- IRCT20191203045594N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
All patients with biopsy-proven squamous cell carcinoma of hypopharynx, nasopharynx, and larynx
Exclusion Criteria
All patients with distant metastasis
Hypersensitivity to metformin
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The complete response. Timepoint: 12 weeks after the intervention. Method of measurement: Spiral CT scan.;Toxicity. Timepoint: Weekly. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE).
- Secondary Outcome Measures
Name Time Method