Fluid Status and Body Composition Analysis in Patients After Cardiac Surgery Assessed by Bioelectrical Impedance Method and Its Impact on Postoperative Morbidity and Mortality
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiopulmonary Disease
- Sponsor
- University Medical Centre Ljubljana
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Fluid distribution during the early postoperative period (≤ 5 days)
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
Evaluation of fluid status in cardiac surgery patients using bioelectrical impedance and its impact on postoperative morbidity and mortality
Detailed Description
Hydration and fluid balance dynamics after cardiac surgery is complex and requires comprehensive knowledge of bluid balance dynamics. Surgical trauma, anaesthesia and use of cardiopulmonary bypass significantly influence postoperative fluid status. Deviations from normal values on the other hand can be related to increase in morbidity and mortality. The purpose of this prospective observational clinical study is to assess fluid status using bioelectric impedance in patients undergoing cardiac surgery and to evaluate its impact on postoperative morbidity and mortality.
Investigators
Laura Kekec
Principal Investigator
University Medical Centre Ljubljana
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Fluid distribution during the early postoperative period (≤ 5 days)
Time Frame: Perioperative period (preoperatively, on the first, third, and fifth postoperative day)
Bioelectrical impedance vector analysis
Secondary Outcomes
- Impact of fluid distribution/fluid overload on 30-day postoperative mortality(On day 30)
- Impact of fluid distribution/fluid overload on duration of postoperative mechanical ventilation(Duration of stay in ICU (estimated to up to 5 days))
- Impact of fluid distribution/fluid overload on length of stay in the intensive care unit(Duration of stay in ICU (estimated to up to 5 days))
- Impact of fluid distribution/fluid overload on 1-year postoperative mortality(At 1 year postoperatively)
- Impact of fluid distribution/fluid overload on postoperative complications (myocardial infarction, cardiogenic shock, vasoplegia, atrial fibrillation, heart failure, bleeding, infections, delirium)(Up to 1 year after the operation)
- Impact of fluid distribution/fluid overload on length of hospitalisation(Duration of hospital stay (up to 1 month))