Fluid Status and T1-mapping by CMR

• Conditions: Valvular Heart Disease; Heart Diseases; Heart Failure
• Interventions: Diagnostic Test: Bioimpedance spectroscopy

• Registration Number: NCT03372512
• Lead Sponsor: Medical University of Vienna

Brief Summary

It is unclear to what extent systemic fluid overload has an impact on T1-mapping results by cardiovascular mangetic resonance imaging.

In this study, patients will undergo body composition monitoring assessing systemic fluid overload and T1-mapping using MOLLI by cardiovacular magnetic resonance imaging in order to investigate a possible association with each other.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-12-07
• Study First Submitted QC: 2017-12-12
• Study First Posted: 2017-12-13
• Study Start: 2018-05-08
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-12
• Last Update Posted: 2019-08-14
• Primary Completion: 2020-12-15
• Study Completion: 2020-12-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• written informed consent
• patient undergoing cardiovascular magnetic resonance imaging

Read More

Exclusion Criteria

• Unwillingness to participate
• pregnancy

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Fluid overload (Liters) ≥ median	Bioimpedance spectroscopy	-
Fluid overload (Liters) < median	Bioimpedance spectroscopy	-

Primary Outcome Measures

Name	Time	Method
Native T1-mapping	baseline	Association of fluid overload and native T1 values of left ventricular myocardium
Extracellular Volume by Cardiovascular magnetic resonance imaging	baseline	Association of fluid overload and extracellular volume of left ventricular myocardium

Trial Locations

Locations (1)

Medical University of Vienna; 🇦🇹 Vienna, Austria