Could supported weight loss reduce womb cancer surgery complications?

Not Applicable

• Conditions: Womb cancer; Cancer

• Registration Number: ISRCTN13577800
• Lead Sponsor: niversity of Oxford

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-10-27
• Last Update Posted: 13 November 2023
• Study Completion: 2028-02-29

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 72

Inclusion Criteria

For patients:
1. Participant is willing and able to give informed consent for participation in the study.
2. Able to communicate in English or has a relative/friend/carer acting as interpreter.
3. Aged 18 years or above.
4. BMI >= 28 kg/m² (or BMI >= 25 kg/m² for people of Black, Asian, or minority ethnic origin).
5. Planned for curative elective surgery for endometrial cancer.
6. Performance status 0-2.

For staff:
1. Any research or clinical staff involved in the study and recruitment process

Exclusion Criteria

For patients:
1. > = 10% self-reported weight loss in the 6 months before the screening visit
2. < 20 days from the screening visit until surgery.
3. Having allergy to soy.
4. Documented stage 4-5 kidney disease.
5. Documented severe heart failure (defined as New York Heart Association grade 3 or 4).
6. Previous bariatric surgery.
7. Type 1 diabetes.
8. Currently on insulin with a previous episode of diabetes ketoacidosis.
9. Currently on warfarin.
10. Pregnancy, breastfeeding, or planning pregnancy during the course of the trial.
11. Any other significant disease or disorder which, in the opinion of the Investigator or healthcare professional, may either put the participants at risk because of participation in the trial, or may influence the result of the trial, or the participant’s ability to participate in the trial.
12. Currently taking part in other interventional clinical trials unless agreed in advance by all trial teams (participation in observational studies is allowed).

For staff:
1. No exclusions

Study & Design

• Study Type: Interventional
• Study Design: Not specified