High Doses Vitamin C and Tissular Repair in Surgical Patients
- Conditions
- Tissue Damage
- Registration Number
- NCT04896359
- Lead Sponsor
- Universidad San Francisco de Quito
- Brief Summary
This is a prospective, randomize, double-blind, and placebo-controlled study to evaluate in patients with clinical criteria for any of the following open surgical procedure: (1) cesarean section; (2) aesthetic surgery like abdominoplasty; (3) orthopedic surgery; and (4) abdominal open surgery \[excluding laparoscopic procedures\] will be invited to receive either a high dose of vitamin C (12.5 g) three times (48 h pre-surgery, immediately before surgery and 48 h post-surgery) or its placebo, to evaluate the tissue repair process using an international validated instrument named Patient and Observer Scar Assessment Scale.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
- Older than 18 years.
- Susceptible for any of the following surgical procedures: (1) cesarean section; (2) aesthetic abdominal plastic surgery; (3) orthopedic prosthetic replacement surgery
- Voluntary consent to participate
- Known allergy to the vitamin C
- Known problems with wounds healing
- Kidney disease (including lithiasis) or gout
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Evaluation of linear scars third assessment, three months after surgery Patient and Observer Scar Assessment Scale (it evaluates in a 0 to 10 scale: vascularity, pigmentation, thickness, relief, pliability and surface area)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hospital de los Valles
🇪🇨Quito, Pichincha, Ecuador
Hospital de los Valles🇪🇨Quito, Pichincha, Ecuador