Comparison of the Effects of Dexmedetomidine and Fentanyl-Midazolam Combination on Mitigating Stress Response for Microlaryngoscopy

Phase 2

Recruiting

• Conditions: Microlaryngoscopy.; Other diseases of larynx; J38.7

• Registration Number: IRCT20210117050057N2
• Lead Sponsor: Magrabi Eye, ENT and Dental Center, Doha, Qatar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Age 18-65 years
ASA grade I/III
Scheduled for microlaryngoscopy

Exclusion Criteria

Patients with known allergy to study drugs
Coronary artery disease
Pulmonary disease
Arrhythmia
Pregnancy
Renal impairment

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hemodynamic stress response. Timepoint: Intraoperative. Method of measurement: Systolic Blood Pressure , Mean Arterial Pressure, Heart Rate were monitored.

Secondary Outcome Measures

Name	Time	Method
Intraoperative requirement of propofol. Timepoint: Intraoperative. Method of measurement: Total dose guided by bispectral index.;Sedation. Timepoint: Postoperative. Method of measurement: Ramsay score.;Analgesia. Timepoint: Postoperative. Method of measurement: Visual Analogue Scale.;Anesthesia duration. Timepoint: Intraoperative. Method of measurement: Time measurement.;Recovery time. Timepoint: Postoperative. Method of measurement: Time measurement.