Probiotics Regulates Skin Care in Children

Not Applicable

Recruiting

• Conditions: Skin Care; Probiotics; Children
• Interventions: Dietary Supplement: Placebo; Dietary Supplement: Probiotics Lactobacillus salivarius AP-32; Dietary Supplement: Probiotics Lactobacillus rhamnosus LGG; Dietary Supplement: Probiotics Bifidobacterium animalis subsp. lactis CP-9

• Registration Number: NCT05005611
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Probiotics, a component that is generally referred to as a living microorganism or a microorganism present in a host. Most studies have shown that probiotics can regulate immune function in the body. Many studies have attempted to understand whether the use of probiotics can prevent allergic diseases or not.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-31
• Study First Submitted: 2021-08-10
• Study First Submitted QC: 2021-08-12
• Study First Posted: 2021-08-13
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-17
• Last Update Posted: 2023-07-19
• Primary Completion: 2024-07-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 148

Inclusion Criteria

• Estimated by PI.

Exclusion Criteria

• Be allergic to medicine
• Take medicine like immune inhibition, or steroid injection in two weeks
• Participate in another clinical research or immune therapy in one month
• Have severe disease
• Inappropriate for this trial judged by PI

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	-
Probiotics Lactobacillus salivarius AP-32	Probiotics Lactobacillus salivarius AP-32	-
Probiotics Lactobacillus rhamnosus LGG	Probiotics Lactobacillus rhamnosus LGG	-
Probiotics Bifidobacterium animalis subsp. lactis CP-9	Probiotics Bifidobacterium animalis subsp. lactis CP-9	-

Primary Outcome Measures

Name	Time	Method
Skin severity scoring	3 months	According to the scale to estimate skin severity

Secondary Outcome Measures

Name	Time	Method
Life quality	3 months	The questionnaire of life quality in three months.
NGS in gastrointestinal tract	3 months	The difference of NGS ( Next Generation Sequence ) in gastrointestinal tract between 0 month and the 3rd month.
Blood analysis	3 months	ELISA analysis

Trial Locations

Locations (1)

Kaohsiung Chang Gung Memorial Hospital; 🇨🇳 Kaohsiung City, Taiwan