A Formative Evaluation For Improving Breast Cancer Hormone Receptor Testing in Tanzania

Recruiting

• Conditions: Breast Cancer
• Interventions: Behavioral: Focus group; Behavioral: Organizational Readiness for Implementing Change

• Registration Number: NCT05438511
• Lead Sponsor: Memorial Sloan Kettering Cancer Center

Brief Summary

The purpose of this study is to learn more about the challenges with breast cancer diagnosis in Tanzania and the support available to improve this process.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-06-17
• Study First Submitted QC: 2022-06-24
• Study First Posted: 2022-06-30
• Study Start: 2023-04-13
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-14
• Last Update Posted: 2025-05-18
• Primary Completion: 2026-04
• Study Completion: 2026-04

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Breast cancer survivor, patient advocate or key healthcare personnel

  • Key healthcare personnel are defined as hospital and laboratory leaders, pathologists, laboratory scientists and technicians, oncologists, nurses, and surgeons, with:
  • >12 months of employment at the affiliated institution
  • Administrative or clinical involvement in the delivery of breast cancer care services.

• Age 18 years and above

• Permanent residents or citizens of Tanzania

• Participant and/or LAR willing and able to consent

• Fluent in Swahili and/or English by self-report

Participant

Exclusion Criteria

• Key stakeholder not residing at their particular institutions during data collection will be excluded.

Eligibility criteria for Chart Reviews

Inclusion Criteria for chart review:

• Age 18 years and above
• Permanent residents or citizens of Tanzania
• Received breast cancer diagnosis

Exclusion Criteria for chart review: none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Participants of focus groups	Organizational Readiness for Implementing Change	Breast cancer survivor, patient advocate or key healthcare personnel including hospital and laboratory leaders, pathologists, laboratory scientists and technicians, oncologists, nurses, and surgeons
Participants of focus groups	Focus group	Breast cancer survivor, patient advocate or key healthcare personnel including hospital and laboratory leaders, pathologists, laboratory scientists and technicians, oncologists, nurses, and surgeons

Primary Outcome Measures

Name	Time	Method
Identify barriers for breast cancer diagnosis in Tanzania.	1 year	Depending on results of this initial evaluation, either additional data will be collected, or if successful, will use the data to begin identifying context-specific implementation strategies using the 'Implementation Mapping' framework1 . In a future protocol, these data will then be used to develop a strategy for an intervention that addresses urgent evidence-to-practice gaps in breast cancer diagnosis in Tanzania, and has the potential to help patients with breast cancer in sub-Saharan Africa (SSA) in the future. The collection of this key information will assist us and our collaborators to generate background data that can be used to develop and/or complement future clinical trials.

Trial Locations

Locations (2)

Memorial Sloan Kettering Cancer Center (All Protocol Activities); 🇺🇸 New York, New York, United States

Muhimbili University of Health and Allied Sciences; 🇹🇿 Dar Es Salaam, Tanzania