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Pilot Functional Imaging Study to Evaluate Mechanisms Underlying Chronic Pain in Breast Cancer Patients

Completed
Conditions
Pain
Breast Cancer
Registration Number
NCT01639417
Lead Sponsor
Lynn Henry
Brief Summary

The purpose of this study is to better understand why some women with breast cancer develop chronic pain.

Detailed Description

Women with breast cancer who either have chronic pain or who do not have chronic pain will be asked to enroll. Those who participate will have pictures taken of their brain using MRI when they are lying still and also when pressure is being applied to their thumbnails. These pictures will be compared to patients without breast cancer who do not have pain and to those who have other types of pain, such as fibromyalgia. By taking and analyzing these pictures the investigators hope to understand more about why breast cancer survivors develop pain after their diagnosis and treatment. In the future the investigators hope to better treat the pain or possibly even prevent the pain from occurring in the first place.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
39
Inclusion Criteria
  • Breast Cancer Survivor with and without chronic pain
  • Able to undergo MRI
Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Determination of differences in pain sensitivity and functional MRI in different groups of patients.6 months

The primary objective of this pilot trial is to determine if there may be differences in mechanical pain sensitivity and functional MRI brain activation patterns in breast cancer survivors with chronic pain as compared to breast cancer patients without chronic pain, to patients with fibromyalgia, or to healthy controls.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Michigan Comprehensive Cancer Center

🇺🇸

Ann Arbor, Michigan, United States

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