Effect of transcranial Direct Current Stimulation (small battery operated devices delivering 2mA of current to specific regions of the brain) on cognitive functions and symptoms of depression in patients suffering from depressio
- Conditions
- Health Condition 1: F330- Major depressive disorder, recurrent, mildHealth Condition 2: F331- Major depressive disorder, recurrent, moderateHealth Condition 3: F320- Major depressive disorder, singleepisode, mildHealth Condition 4: F321- Major depressive disorder, singleepisode, moderate
- Registration Number
- CTRI/2019/05/019300
- Lead Sponsor
- Manipal University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients diagnosed with mild and moderate depression according to ICD 10 criteria
2. Patients who are able to give written informed consent to undergo tDCS
3. Patients of either gender
4. Patients who have been administered a stable dose of antidepressants and/or antipsychotic/mood stabilizers for at least 2 weeks
5. At least five years of formal education (primary level)
1. Psychiatric co-morbidities, which will be ruled out using the MINI PLUS scale (Excluding Tobacco Dependence Syndrome)
2. Patients not willing to give consent
3. Advanced liver, kidney, cardiac or pulmonary diseases
4. Contraindications to tDCS e.g. metal or medical devices implanted in the body
5. Patients with a history of seizures
6. Patients in remission i.e. patients with a baseline HAM-D score of <= 7 and IDS score of <=14
7. Patients with Severe Depression
8. Patients with a history Bipolar disorder
9. Patients on Benzodiazepines at the time of tDCS procedure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in neurocognitive functions in patients receiving tDCSTimepoint: 4 weeks
- Secondary Outcome Measures
Name Time Method Reduction in depressive score â?¥50% HAM-D and IDS scores in patients receiving tDCS. <br/ ><br>Timepoint: 4 weeks